Choline is an essential nutrient and is associated with a number of positive health effects including possibly preventing fatty liver disease and cognitive decline in the elderly. Only 5 comparisons from 4 articles 9101113 presented results of dietary consumption of choline and betaine combined and cancer risk.
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Although this form of cancer can be treated if it is detected early preventing the cancer from developing in the first place is a better option.
Choline cancer risk. One study found that men with the highest choline intake 500 mgday had a 70 increased risk of incident lethal prostate cancer compared with men with the lowest intake 300 mgday the top 5 foods contributing to choline in the diets of the participants were whole eggs beef skim milk reduced fat milk and poultry without skin. In the case only survival analysis we observed 271 lethal cases during 33679 person years. Also a peer reviewed study published by the national institute of health shows that breast cancer risk was reduced 24 among women with a high dietary intake of choline.
Dietary deficiency of choline in humans results in fatty liver liver damage and muscle damage. Choline intake and risk of lethal prostate cancer. These studies were done prospectively which is strong.
High choline diet increases risk of prostate cancer by 70. Choline and prostate cancer. In a study recently published in the american journal of clinical nutrition.
Prostate cancer is one of the leading illnesses in men. High intake of eggs and chicken were particularly associated with increased risk of men who already had prostate cancer developing aggressive disease as evidenced by the cancer spreading or killing them among other bad outcomes. Postdiagnostic choline intake was not statistically significantly associated with the risk of lethal prostate cancer hr for quintile 5 compared with quintile 1.
While the link between choline and fatal prostate cancer is becoming clear the risk benefit analysis remains murky. Choline is necessary for the structure and function of all cells. Choline plus betaine consumption and cancer risk.
For the highest versus the lowest choline plus betaine consumption the pooled rr was 060 95ci 040 to 090.
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