Efficacy and safety ratings were done weekly. Choline for bipolar disorder.
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Home bipolar disorder nutritional supplements for bipolar disorder.
Choline and inositol for bipolar. The point is that the combination of choline and inositol tends to produce a fairly neutral and balanced effect on ones mood. Twenty four consenting adult men and women with dsm iv bipolar depression bipolar i 21. Previous posts briefly reviewed conventional pharmacologic treatments uses of select amino acids and omega 3.
At 15 to 30 gm per day might reduce the severity of both mania and depressed mood in bipolar patients and that. Bipolar ii 3 were randomly assigned to receive either 12 g of inositol or d glucose as placebo for 6 weeks. Inositol monophosphatase is a phosphodiesterase enzyme that is often called impase.
Since this page was originally created i have found more research that suggests the opposite may be true and that supports a low inositol diet for bipolar disorder. It works in the pi phosphatidylinositol pathway of signaling and accommodates a variety of vital cellular functions including apoptosis growth and repair processing information and secreting. One of the active ingredients in lecithin.
At this time the evidence appears too mixed to suggest a definate and positive inositol and bipolar nexus. Choline inositol lecithin for detoxification both choline and inositol are what are called lipotrophic substances lipo means lipids or fatsoils and trophic means attracted to. Its effectiveness for bipolar symptoms is unknown.
Inositol and choline may be beneficial for a variety of mental health problems. The inositol and bipolar connection seems to exist but is still unclear. The body uses choline and inositol to synthesize lecithin but it can also operate in reverse metabolizing choline from lecithin.
This post is the fourth in a series on bipolar disorder. The choline inositol lecithin connection is unique in that it works both ways when it comes to production. This pilot study evaluated its potential efficacy and safety in bipolar depression.
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