123 cyclothiazide is a benzothiadiazide that acts as a potentiator of ampa receptors positively modulating its response to glutamic acid ec 50 38 um. 456 it blocks the rapid agonist induced desensitization of ampa receptors resulting in enhanced excitatory activity.
Depression Is Reduced By Cyclothiazide All Experiments Were
Depression Is Reduced By Cyclothiazide All Experiments Were
Rcsb Pdb 3tkd Crystal Structure Of The Glua2 Ligand Binding
We prepared a fluorescent microscope with a perfusion system to smoothly exchange a buffer. Cyclothiazide is 34 dihydro 2h 124 benzothiadiazine 11 dioxide substituted at positions 3 5 and 6 by a 2 norbornen 5 yl group chlorine and a sulfonamide group respectivelya thiazide diuretic it has been used in the management of hypertension and oedema.
Cyclothiazide Semantic Scholar
Cyclothiazide Semantic Scholar
Effects Of Cyclothiazide On Glur1 Ampa Receptors Pnas