Choline is a b complex vitamin found in the lecithin of many plants and animals. It is also used for depression memory loss alzheimers disease and dementia huntingtons chorea tourettes disease a brain disorder called cerebellar ataxia certain types of seizures and a mental condition called schizophrenia.
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Choline supplies methyl groups essential for converting homocysteine to methionine.
Choline heart disease. Some studies have shown that choline and lecithin can help to reduce blood cholesterol and risk for heart disease but different studies have yielded inconsistent results so more research is still needed before doctors will begin to prescribe choline for its ability to lower ldl bad cholesterol and trigylcerides. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Choline tmao and heart health.
In addition to assuring your tmao levels are low to reduce heart disease risk be aggressive about losing weight and lowering cholesterol and blood pressure. Low levels of choline may thus lead to homocysteine buildup and increase the risk of heart disease and stroke in some people 1 75 76 77. But a new paper suggests supplemental choline is clot enhancing.
The institute of medicine notes that is prevents some chronic diseases. Heart disease and stroke. Moreover if eating choline rich foods did increase the risk of heart disease via tmao or any other mechanism wed expect to see higher rates of chd in those that eat more eggs.
It may be of concern then that a recent paper published in nature suggests that dietary choline may be contributing to heart disease. Foods with substances that block tmao formation include cold pressed extra virgin olive oil balsamic vinegars and red wines. With reviewing studied researches on dietary choline and betaine intake and cardiovascular diseases it can be concluded that the dietary choline and betaine intake had no significant association with incidence of cvd49 52 however more intakes of these substances were associated with significant reduction of serum inflammatory markers54 high dietary choline and betaine intakes similar to supplementation would reduce thcy levels in healthy and hyperhomocysteinemia people4549.
In almost 4k african american patients higher intake of choline lowered the risk of stroke. Choline is used for liver disease including chronic hepatitis and cirrhosis. Yet numerous studies have failed to find any such association.
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