Med tr prom ekol12. 16 21 2001nchial obstruction in chronic dust bronchitis in workers of deep coal mines.
Choline Chloride
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A basic constituent of lecithin that is found in many plants and animal organs.
Choline chloride structure. 11c choline chloride is a quaternary ammonium salt that is the chloride salt of 11c cholinean intravenous radioactive diagnostic agent used as a tracer during positron emission tomography scans to help detect sites of recurrent prostate cancer. Choline chloride is an organic compound with the formula ch33nch2ch2ohcl. Articles of choline chloride are included as well.
It is a white water soluble salt used mainly in animal feed. Choline chloride is an organic compound and a quaternary ammonium salt an acyl group acceptor and choline acetyltransferase substrate also is an important additive in feed especially for chickens where it accelerates growth. It is bifunctional containing both quaternary ammonium salt and an alcohol.
Chemsrc provides choline chloridecas67 48 1 msds density melting point boiling point structure formula molecular weight etc. It is important as a precursor of acetylcholine as a methyl donor in various metabolic processes and in lipid metabolism. Oral 20 choline chloride solution lowers bronchospasm in dust bronchitis patients with decreased serum subunits of phosphatidyl inositol and increased serum levels of phosphatidyl cholinekorzh ev et al.
Test solution transfer about 500mg of choline bitartrateaccurately weighedto a centrifuge tubeadd 20mlof waterand swirl to dissolveadd 05mlof potassium chloride solution 75in 25centrifugeand transfer 10mlof the supernatant to a 24 mlscrew capped vialdry at 120 for 2hoursadd 400mg of 35 dinitrobenzoyl chloride and 10mlof acetonitrileand mixcap the vialand heat at 55 for 1hourcool to room temperatureadd 5mlof waterand allow to stand for 2minutesquantitatively transfer. Choline chloride inn rn. The cation is choline which occurs naturally.
Standard solution transfer an accurately weighed amountnot more than 100mgof usp choline chloride rs to a 24 mlscrew capped vialand add 400mg of 35 dinitrobenzoyl chloride and 10mlof acetonitrilecap the vialheat to 55 and continue heating for 1hourcool to room temperatureand add 5mlof waterallow to stand for 2minutesquantitatively.
Choline Linus Pauling Institute Oregon State University
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Choline Chloride Bic0605 67 48 1 From Apollo Scientific
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