Poisons and toxins that attack the enzyme cause acetylcholine to accumulate in the nerve synapse paralyzing the muscle. Since acetylcholinesterase has an essential function it is a potential weak point in our nervous system.
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Acetylcholinesterase hgnc symbol ache.
Acetylcholinesterase. How to use acetylcholinesterase in a sentence. Acetylcholinesterase ase til kolin ester as an enzyme present in nervous tissue muscle and red blood cells that catalyzes the hydrolysis of acetylcholine to choline and acetic acid. Acetylcholinesterase is involved in the hydrolysis of acetylcholine an essential neurotransmitter of the central nervous system into choline figure 9this enzyme catalyzes the hydrolysis of the neurotransmitter acetylcholine at neuronal synapses and at neuromuscular junctions at the end of the signaling process.
An enzyme that breaks down the neurotransmitter acetylcholine at the synaptic cleft the space between two nerve cells so the next nerve impulse can be transmitted across the synaptic gap. Ec 3117 also known as ache or acetylhydrolase is the primary cholinesterase in the body. This enzyme is present throughout the body but is particularly important at the myoneural junction where the nerve fibers terminate.
It is an enzyme that catalyzes the breakdown of acetylcholine and of some other choline esters that function as neurotransmittersache is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type where its activity serves to. Pesticides of the organophosphate and carbamate types act to paralyze and kill insects by inhibiting their acetylcholinesterase. Acetylcholinesterase definition is an enzyme that occurs chiefly in cholinergic nerve endings and promotes the hydrolysis of acetylcholine.
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