Sunday, January 5, 2020

Ampakines Cognitive Enhancement

Neurobiological considerations and modeling studies suggest that the drugs in addition to their effects on disturbed behavior. Ampakines enhance the functioning of a receptor called the ampa receptor which plays a key role in memory formation and communication within and between different regions of the brain.

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Cognitive Enhancement

Opinion ampakines and the threefold path to cognitive enhancement.

Ampakines cognitive enhancement. Ampakines are the first peripherally administered drugs that increase excitatory monosynaptic responses in the brain. Ampakines are effective in animal models of neuropsychiatric disorders and have produced positive results in a small number of human studies. The hope and promise of ampakines is that they will produce cognitive benefits when used as drugs.

Ampakine cognitive enhancement research have also become a point of interest for the american military. Because of this effect the compounds improve communication in complex networks potently facilitate long term potentiation ltp and induce the expression of neurotrophic factors. Ampakines and the threefold path to cognitive enhancement.

Ampakines are a class of pharmacological agents that act as positive modulators of ampa receptors to enhance excitatory glutamatergic neurotransmission baumbarger muhlhauser yang nisenbaum 2001. A large body of evidence suggests that the extracellular portion of the ampa receptor composed of the lbd and ntd mediates complex regulation in gating mechanisms of the receptors and in kinetics and strength of glutamatergic synaptic transmission18. Miu et al 2001.

Ampakines like aniracetam and sunifiram seem to have the same stimulant properties as the amphetamine class of drugs without the same risk of negative side effects. Ornstein et al 2000. Ampakines influence the receptors.

Cognitive Enhancement

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