This group typically excludes compounds in which either benzene is fused to another ring or includes a heteroatom or where the methane connects to three or four benzenes. There are two independent molecules in the asymmetric unit.
A Process For The Preparation Of Modafinil Patent 1503983
Us7186860b2 Process For The Preparation Of 2 Diphenylmethyl
Modafinil Wikipedia
Modifinil is a compound benzhydryl sulfinyl acetamide discovered in the 1970s and initially offered as an experimental treatment for narcolepsy.
Benzhydryl sulfinyl acetamide. The benzhydryl compounds are a group of organic compounds whose parent structures include diphenylmethane with any number of attached substituents including bridges. 2 diphenylmethylsulfinyl acetamide history modafinil was originally developed in france by neurophysiologist and emeritus experimental medicine professor michel jouvet and lafon laboratories. Modafinil has been approved by the united states food and drug administration for use in the treatment of excessive daytime sleepiness associated with narcolepsy and is marketed under the.
Modafinil originated with the late 1970s invention of a series of benzhydryl sulfinyl compounds including adrafinil which was first offered as an experimental treatment for narcolepsy in france in 1986. Modafinil c 15 h 15 no 2 s also known as 2 benzhydrylsulfinyl acetamide or 2 diphenylmethylsulfinyl acetamide is a synthetic acetamide derivative with wake promoting activity the structure and synthesis of which has been described in french patent no. Acetamide 2 r diphenylmethylsulfinyl n hydroxy c15h15no3s cid 25271624 structure chemical names physical and chemical properties classification.
Modafinilcrl 40476 cep 1538 is a central nervous system vigilance promoting agent which posseses neuroprotective properties. Jaydev chem has been one of the fastest growing pharmaceutical intermediate manufacturing company in gujarat. We aim to be a leading pharmaceutical intermediates manufacturing company in india.
78 05 510 and in us. Narcolepsy itself is a serious neurological disorder disrupting sufferers sleep patterns. Modafinil was found to inhibit kca31 currents in a concentration dependent manner and the half maximal inhibition ic50 of modafinil for the current inhibition was 68.
World class developer manufacturer of differentiated apis in 50 countries 198 dmfs worldwide. The title compound c15h14no2s was prepared by the esterification of benzhydrylthioacetic acid followed by amidation and oxidation. N benzhydryl 2 pyrrolidin 1 yl acetamide c21h24n2o5 cid 24746941 structure chemical names physical and chemical properties classification patents literature biological activities safetyhazardstoxicity information supplier lists and more.
To become a significant global player by innovative technology and providing high quality cost effective and affordable products. Ball and stick model of the benzhydryl radical the benzhydryl radical can be abbreviated chph 2 or bzh.
2 Diphenylmethyl Sulfinyl Acetamide Powder 68693 11 8
Developed Formula Of Modafinil 2 Diphenylmethyl Sulfinyl N
S Modafinil
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