Treated animals displayed an increase in the dopamine receptor densities of 11 for those receiving 100 mg kg 1 and 18 for those receiving 500 mg kg 1 as compared to the control aged animals that had received no cdp choline. I dont know how to translate the mice dosage to human dosage though.
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Lets be honest this bit of information is of limited practical use.
Cdp choline dopamine receptor density. Control animals showed from 2 months to 19 months of life a 28 decrease in the receptor density. It is an equivalent of taking uridine and eating eggs the mice given cdp choline showed increased dopamine receptor density. But cdp choline citicoline has had a permanent long term effect on me and i believe its related to its effect or modulation of receptors such as dopamine receptors.
What this means to you. Is an intermediate step in the formation of phosphatidylcholine pc from choline not a derivative as alpha gpc is. In the one treated group a dose of 100mgkg was used and an 11 increase of da receptor densities was found.
The nucleoside uridine a metabolite of cdp choline may be involved. Cdp choline turns into uridine and choline in the body. Many studies of cdp choline mention effects on dopamine receptors.
Otherwise known as citicoline cytidine diphosphate sodium choline cdp choline sodium 2. In one study cdp choline was provided to aged rats over the course of seven months. Citocholine leads to a higher density of dopamine receptors.
After seven months levels of striatal da were measured. Cdp choline is capable of raising dopamine receptor density or the overall number of dopamine activation points in the brain. Also it is thought to increase the density of dopamine receptors in the brain.
Citicoline also known as cdp choline cytidine diphosphate choline is a popular nootropic known to improve cognitive function and brain health. It mainly increases the levels of acetylcholine in the brain thus improving memory and communication between neurons.
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