Showing posts with label 2a peptide ribosome skipping. Show all posts
Showing posts with label 2a peptide ribosome skipping. Show all posts

Thursday, October 3, 2019

2a Peptide

2a self cleaving peptides or 2a peptides is a class of 1822 aa long peptides which can induce the cleaving of the recombinant protein in cell. For example f2a would be a 2a peptide from the foot and mouth disease virus and gf2a would be the f2a with a gsg linker.

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These limitations can be overcome by a 2a peptide a self cleaving small peptide first identified by ryan and colleagues in the foot and mouth disease virus fmdv a member of the picornavirus.