The human body can produce choline by methylation of phosphatidylethanolamine by n methyltranferase to form phosphatidylcholine in the liver or it may be consumed from the diet. Choline is an organic water soluble compound.
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Phosphatidylcholine is a chemical contained in eggs soybeans mustard sunflower and other foods.
Choline liver complex. There are reports that taking high doses of choline might be helpful for some people with a type of seizure called complex partial seizures. Choline deficient diets including those that are also deficient in methionine have long been utilized to study the mechanisms of fatty liver disease and its progression because such diets recapitulate many of the phenotypes seen in humans with nafld including an accumulation of triglycerides in the liver 5 31. However it is often grouped with the vitamin b complex due to its similar properties and functions.
It is found naturally in the body in all cells. Without adequate dietary intake of choline there is a higher than normal risk of chronic liver damage and eventual liver failure. Choline is a component of phosphatidylcholine which is a component of lecithin.
The function of choline is complex and involves interplay with folate methionine and vitamin b 12. This supplement provides thiamin vitamin b1 and folic acid vitamin b9 which contribute to normal energy yielding metabolism. Although small amounts of it can be made in the liver the majority must be obtained from the diet.
Choline is also a precursor of acetylcholine a neurotransmitter vital to nerve and muscle function and a component of lecithin which is critical to normal liver metabolism. Although not technically a vitamin by strict definition this organic compound is required for lifes most quintessential functions including basic cellular structure nutrient transport and metabolism. Hepatitis and other liver disorders.
Normal liver function choline contributes to the maintenance of normal liver function. It is classified as neither a vitamin nor a mineral. Energy release the liver stores nutrients and regulates the supply of energy to the body.
The term phosphatidylcholine is sometimes used interchangeably with lecithin although the two are different. Choline is an essential water soluble nutrient that is usually grouped in as part of the b vitamin complex.
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