The body manufacturers a small amount of choline but it is usually not. Choline is a macronutrient thats important for liver function normal brain development nerve function muscle movement supporting energy levels and maintaining a healthy metabolism.
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Figure 1 From Choline And The Brain An Epigenetic Perspective
It has been established that choline is necessary for optimal cognitive function.
Choline function. Choline also plays important roles in modulating gene expression cell membrane signaling lipid transport and metabolism and early brain development 12. Choline acetyltransferase catalyzes the acetylation of choline to acetylcholine and acetylcholine esterase hydrolyzes acetylcholine to choline and acetate. Choline is an organic water soluble compound.
Most authorities classify choline as an essential nutrient or micronutrient. Choline is an essential nutrient 2. Because of this choline is important in any health concerns involving the liver such as cirrhosis or alcoholism.
Without adequate dietary intake of choline there is a higher than normal risk of chronic liver damage and eventual liver failure. Choline is a precursor for acetylcholine an important neurotransmitter synthesized by cholinergic neurons and involved in muscle control circadian rhythm memory and many other neuronal functions. Although small amounts of it can be made in the liver the majority must be obtained from the diet.
Other research suggests choline can improve visual memory. Its role in the body is complex. Choline is required by the body for a number of important processes including liver protection cell membrane structure and maintaining neurotransmitter functioning.
It is classified as neither a vitamin nor a mineral. This means its required for normal bodily function and human health. Choline is present in the form of phosphatidycholine a compound that makes up the structural component of fat and thus can be found in different types of foods that naturally contain certain fats.
It is needed for neurotransmitter synthesis acetylcholine cell membrane signaling phospholipids lipid transport lipoproteins and methyl group metabolism homocysteine reduction. Choline is also good for the brain. Early research suggests that taking a single dose of choline does not improve reaction time reasoning memory or other mental functions.
In addition choline is needed to produce acetylcholine an important neurotransmitter for memory mood muscle control and other brain and nervous system functions. Choline is also a precursor of acetylcholine a neurotransmitter vital to nerve and muscle function and a component of lecithin which is critical to normal liver metabolism. Early research suggests that inhaling choline might improve symptoms of bronchitis caused by dust.
Choline was officially recognized as an essential nutrient by the institute of medicine in 1998. Choline plays a major role in transport of fats and fat metabolism.
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