Here the authors show that cx 5461 a small molecule in clinical trials as rna polymerase inhibitor has g4 stablization properties and can be repurposed to target dna repair defective cancers cells. Cx 5461 is a first in class small molecule g quadruplex g4 stabiliser being developed for the treatment of haematological malignancies and solid tumours.
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Control Of Ribosomal Rna Transcription By Nutrients Intechopen
Cx 5461 Dna Rna Synthesis Inhibitor Read Reviews Product Use