One of the main mechanisms of action of piracetam is to improve uptake and utilization of acetylcholine in certain regions of the brain. Cdp choline which is also known as citicoline contains far less of the nutrient per gram which may suggest that it is less effective.
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Piracetam is thought to deplete choline and therefore acetylcholine levels which is why people also supplement with choline.
Choline bitartrate piracetam. Often categorized as a b vitamin choline bitartrate is a water soluble compound that is composed of two separate components choline and bitartrate. Both are bioavailable choline supplements but there are a few subtle differences. Because the piracetam increases acetylcholine uptake the choline combination provided more of the neurotransmitter for the brain to use.
Acetic acid and choline combine to form acetylcholine which is an important neurotransmitter that helps in memory and learning. Choline is a significant nutrient which forms the fatty tissue of brain mainly phosphatidylserine and phosphatidylcholine ie. The ratio of choline to piracetam will depend on the type of choline youre taking.
It helps maintain healthy synapses and membranes in the brain which tend to deteriorate with age. Because the hippocampus is the place where improved memories form it is a good idea to take choline in order to see benefits. Types and sources of choline there are many types of choline that your body can utilize as a precursor for acetylcholine production.
Choline supplements to stack with piracetam. For example piracetam reduces acetylcholine in the hippocampus of rats. Choline bitartrate is a good compliment to a stack including any nootropics from the racetam family.
Choline is a basic dietary compound that is found in many foods containing fats and proteins including eggs wheat germ poultry fish organ meats cruciferous vegetables and peanuts and other legumes. Dosage of piracetam choline stack. If youre taking a weaker form of choline like choline bitartrate or lecithin your cholinepiracetam ratio could range from one milligram of choline for every six milligrams of piracetam to one milligram of choline for every one milligram of piracetam the ratio used in the 1981 rat experiment.
I suspect that the people getting headaches and muscle spasms werent taking enough choline or if they were then they were taking too much. Choline bitartrate piracetam stack proper dosing of any substance depends on many different factors including age weight personal sensitvities and the reason for taking the supplement. We suggest starting with a dose of 500 to 1000 mg daily.
Alpha gpc is about 40 percent choline by weight. The below dosage recommendations and timelines are general guidelines only and your personal dosage levelstimeline may be different. Choline type and dosage.
So stacking piracetam and choline bitartrate boosts acetylcholine activity even more. Some of the information on choline has been a bit contradictory so this is my attempt to understand the risks and benefits of taking choline with piracetam. First of all choline considered a b vitamin is one of the rare substances that can cross the blood brain barrier.
Piracetam for example affects your neuroreceptors for acetylcholine.
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